Symposia No. Room Organiser First Name Surname Symposia Title of the presentations
10.30 – 12.15
New directions in serotonin receptor research and therapeutics
S1 Ballroom Umberto Spampinato, FR Umberto Spampinato S1.1 An Ignored Neural Receptor: the 5-HT2B Receptor Strategies for Therapeutics in Neuropsychiatric Disorders
Haddjeri Nasser S1.2 5-HT3 and 5-HT7 receptor antagonism potentiates antidepressant response
Malgorzata Filip S1.3 5-HT2C receptors as a therapeutic strategy in substance use disorders: focus on cocaine
Francesco Artigas Perez S1.4 Improving speed and efficacy of antidepressant drugs: focus on 5-HT1A and 5-HT3 receptors
Stimulating the Tourette brain – obtaining therapeutic relief and mechanistic insight
S2 Clermont Suite Christine Winter, DE
Laura Pozzi, SE
Christine Winter S2.1 Tourette Syndrome in humans and rats + Brain stimulation techniques in the context of repetitive disorders
Henriette Callesen S2.2 Brain stimulation techniques in the context of repetitive disorders
Laura Pozzi S2.3 Employing optogenetics to elucidate the function of parvalbumin (Pv+) interneurons in the context of Tourette Syndrome
Alberto Priori S2.4 Adaptive deep brain stimulation (aDBS) in Tourette syndrome
Preclinical and translational approaches for the investigation of drug addiction
S3 Marie Louise 1 Marcello Solinas, FR
Nazzareno Cannella
Marcello Solinas S3.1 Persistent neuroadaptations following extensive cocaine self-administration and strategies to boost recovery processes.
Christelle Baunez S3.2 Surgical strategy for addiction based on rats and monkeys studies using deep brain stimulation applied at the level of the subthalamic nucleus
Nazzareno Cannella S3.3 Translational strategies for the development of new medications to treat drug addiction
Rafael Maldonado S3.4 Role of the endocannabinoid system in food-induced addictive-like behavior
The multi-oscillatory circadian network: A key for physiological processes and health
S4 Reading Room Paul Pévet, FR Andries Kalsbeek S4.1 Glucose regulation: A Regulatory Feedback Network of Periphery and Brain
Paul Pevet S4.2 The multi-oscillatory circadian network: A key for physiological processes and health
Challet Etienne S4.3 Rodents models to study the effect on humans of disturbed circadian rhythms and metabolism
El Allali Khalid S4.4 Synchronisation of clocks: The ambient temperature the forgotten “zeitgeber” in mammals
Marie-Paule Felder-Schmittbuhl S4.5 Clocks within the eyes a key for a well functioning retina
Johanna H. Meijer S4.6 Role of the Behavioural feedback on the clock functioning
GPCR heteroreceptor complexes and their adaptor proteins in Parkinson’s disease and schizophrenia
S5 Carlson Suite K. Fuxe, SE Kjell Fuxe S5.1 GPCR heteroreceptor complexes and their adaptor proteins give new integrative mechanisms that may go wrong in Parkinson´s disease and schizophrenia
Fang Liu S5.2 D2-DISC1 protein complexes and their relevance for schizophrenia
Rafael Franco S5.3 GPCR heteroreceptor complexes in models of Parkinson’s disease
Dasiel Oscar Borroto Escuela S5.5 A2A heteroreceptor complexes as therapeutic targets in Parkinson´s disease
Pain and comorbid mental disorders
S6 Marie Louise 2 Marc Landry, FR Frank Porreca S6.1 Reward and motivation in pain and pain relief
Poisbeau Pierrick S6.2 Long-term consequences of perinatal stress on the nociceptive system and pain controls
Bouchatta Otmane S6.3 Alterations of Pain Response in a pharmacological model of an ADHD mouse model
David P. Finn S6.4 Neural sites and mechanisms mediating reciprocal interactions between pain and negative affect
Olivier Roca-Lapirot S6.5 Acquisition of analgesic properties of the CCK system within the amygdala after inflammation
14.00 – 15.45
5-HT2C receptors: widespread control of neurobiological networks: I
S7 Ballroom Giuseppe Di Giovanni, MT Ponimaskin Evgeni S7.1 Comparative analysis on 5-HT2C, 5-HT1A and 5-HT7 receptors on their role in anxiety and depression
Lora Heisler S7.2 Identification of the subset of 5-HT2CRs that control appetite and improve obesity and type 2 diabetes
Kathryn Cunningham S7.3 5-HT2CR Positive Allosteric Modulators: Potential for Therapeutics in Addictive Disorders
Neuroinflammation: disease models, molecular and cellular markers, in vivo monitoring
S8 Clemont Suite Klaus G. Petry, FR
Sylvie Chalon, FR
Klaus G. Petry S8.1 The identification of peptide biomarkers mimicking the complexity of protein interactions at the blood brain barrier in experimental Multiple Sclerosis
Sylvie Chalon S8.2 PET imaging of TSPO to monitor microglia activation and their relevance to disease severity progression in models of Subarachnoid Hemorrhage, Alzheimer and Parkinson diseases
Mario Quarantelli S8.4 MRI modalities to investigate neuroinflammation in experimental and clinical studies
Transcranial Magnetic Stimulation: re-wiring the addicted brain
S9 Carlson Suite Marco Diana, IT Marco Diana S9.1 Exploiting the hypodopaminergic state with TMS in addicts: preliminary observations
Markus Heilig S9.2 Evaluating deep TMS (dTMS) targeting the insula as a potential treatment for alcohol dependence: Design issues and interim results
Abraham Zangen S9.3 Electromagnetic stimulation in the study and treatment of addiction: From animal models to human applications
Antonello Bonci S9.4 From optogenetics to a novel clinical treatment against cocaine use disorders
Oxidative stress implication in neuropathology
S10 Reading Room Amira Zaky, EGYPT Amira Zaky S10.1 APE1 paradox in neuropathic pain management: novel insight on its role as a regulator for microRNAs
Youssef Anouar S10.2 Selenoproteins, oxidative stress and Parkinson’s disease”
Ahmad R Bassiouny S10.3 Neuro-immunological aspects of neurodegenerative disorders
Neurocytoskeleton functions and dysfunctions in neurodegenerative and psychiatric diseases
S11 Marie Louise 1 Annie Andrieux and Marie Jo Mountin, FR C. Laura Sayas Casanova S11.1 Crosstalk between microtubule-associated proteins and +TIPs in neuronal cells: possible implications in neurodegeneration
Marie-Jo Moutin S11.2 Tubulin modifying enzymes in neurodegenerative contexts
Annie Andrieux S11.3 Positive effects of cytoskeleton-related drugs on cognitive abilities in an animal model of psychiatric diseases
Graziella Cappelletti S11.4 Microtubule dysfunction in animal models of Parkinson disease
Márcia Liz S11.5 The cytoskeleton as a novel therapeutic target for old neurodegenerative disorders
Genetic & epigenetic regulation of stress sensitivity from mouse to man: relevance to stress-related disorders
S12 Marie Louise 2 Nicolas Singewald, AT Luisa Pinto S12.1 Genetic and Epigenetic Factors that Modulate Stress-induced neuro- and glio-plasticity: Relevance to Depression
Catherine Belzung S12.2 Epigenetic signature of chronic stress and antidepressant response
Nicholas Singewald S12.3 (Epi)genetic Regulation of Stress and Fear Sensitivity in Mouse Models of Anxiety
Andrew Holmes S12.4 Genetic moderation of stress systems influencing fear extinction
John Cryan S12.5 Microbial Genes, Brain and Behaviour: Regulation of Stress Susceptibility by the Microbiome
16.15 – 18.00
5-HT2C receptors: widespread control of neurobiological networks: II
S13 Ballroom Giuseppe Di Giovanni, MT
Umberto Spampinato, FR
Alfredo Meneses S13.1 Role of 5-HT2 receptors in cognition
Umberto Spampinato S13.2 5-HT2C receptors: a key pharmacological target to control DA neuron activity and DA-dependent behaviors: focus on cocaine
Cristiano Bombardi S13.3 5-HT2A and 5-HT2CR expression profile in young and adult GAERS, NEC and WISTAR rats
The sick brain
S14 Clermont Suite Ana M Sáncehz-Perez
Peter McCormick S14.1 GPCR DIMERS
Ludvic Zrinzo S14.2 A randomised controlled trial of Deep Brain Stimulation in Severe Refractory Obsessive Compulsive Disorder
Ana María Sánchez-Pérez S14.3 Insulin/IGF-1 signalling in pathological situations
Mohamed Najimi S14.4 Neurobehavioural effects of developmental toxicity of heavy metals.
Novel Psychoactive substances: behavioral, neurochemical, molecular effects and underlying mechanisms.
S15 Carlson Suite Maria Antonietta De Luca, IT Michael Baumann S15.1 Neuropharmacology of newly-emerging synthetic stimulants: cathinones and beyond
Liana Fattore S15.2 Effect of the ketamine-like compound methoxetamine on brain reward processing and emotional states
Cristiano Chiamulera S15.3 Ketamine-induced neuroplasticity after acute vs. chronic self-administration in rats: how to keep apart “Dr Jekyll from Mr Hyde”
Colin Davidson S15.4 Potential clinical use of some legal highs
Gaetano Di Chiara S15.5 Third generation synthetic cannabinoids
New perspectives in animal models of depression: pharmacological, anatomical, endocrine and behavioral approaches
S16 Marie Louise 1 Mercè Correa, ES
John D. Salamone, USA
Wolfgang Hauber S16.1 Cognitive flexibility: Corticostriatal circuits and neurochemical modulation in rats
John Salamone S16.2 Effort-related decision making in human depression and animal models: Distinct roles for different monoamines
Mercè Correa S16.3 Impact of exercise on the dopaminergic system and on selection of active vs. passive sources of reinforcement: implications for the treatment of anergia in depression
Antonio Armario S16.4 Chronic unpredictable stress as an animal model of depression: new data and new perspectives
Motor Neuron Disease: Insights into Spinal Muscular Atrophy from Model Organisms
S17 Marie Louise 2 Ruben J. Cauchi, MT Cinzia Cagnoli S17.1 The role of survival motor neuron proteins (FL-SMN and a-SMN) on axonal function and motor neuron phenotype in mouse and cell models of spinal muscular atrophy
Ruben Cauchi S17.2 Drosophila models of spinal muscular atrophy to untangle the function of the survival motor neuron (SMN) complex in the neuromuscular system
Remy Bordonne S17.3 Characterization of survival motor neuron (SMN)-dependent pathways using the S. pombe model organism
Elia Di Schiavi S17.4 Identification of neuroprotective molecules for spinal muscular atrophy using the C. elegans animal model
Molecular insight into pain perception
S18 Carlson Suite Mark Landry, FR
Jacques Noël, FR
Ana Gomis S18.1 Piezo2 and proprioception
Xavier Gasull S18.2 Regulation of TRESK K2P channels and role on pain sensation
Radwani Houda S18.3 Switch from excitatory to inhibitory modulation by group I metabotropic glutamate receptors of nociceptive transmission in a model of inflammatory pain
Jacques Noel S18.4 Non ‐ acidic activation of
acid‐sensing ion channel 3 by lipids